Standard Name	MUB1 1
Systematic Name	YMR100W
Feature Type	ORF, Verified
Description	MYND domain-containing protein required for ubiquitination and turnover of Rpn4p; interacts with Ubr2p (E3) and indirectly with Rad6p (E2); short-lived protein degraded in a Ubr2p/Rad6p dependent manner; similar to the A. nidulans samB gene (1, 2)
Name Description	MUlti Budding 1

Chromosomal Location	ChrXIII:466300 to 468162 | ORF Map | GBrowse

	View Computational GO annotations for MUB1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	protein monoubiquitination (IDA, IMP) regulation of cell budding (IMP, ISS)
Cellular Component
Manually curated	cellular_component unknown (ND)

Classical genetics
null	bipolar budding pattern: increased cellular morphology: abnormal metal resistance: increased proteasome holocomplex activity: increased proteasome subunits accumulation: increased Rpn4p accumulation: increased Rpn4p modification: absent replicative lifespan: increased resistance to tunicamycin: increased resistance to L-canavanine: increased viable
Large-scale survey
null	glycogen accumulation: increased inositol excretion: increased competitive fitness: decreased Rpn4p11-229-His3 accumulation: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to paromomycin: decreased resistance to neomycin: decreased resistance to arsenite(3-): increased resistance to quinine: increased resistance to tacrolimus (anhydrous) and tunicamycin: increased resistance to camptothecin: increased resistance to cycloheximide: increased resistance to caffeine: increased resistance to fluconazole: increased resistance to methyl methanesulfonate: increased resistance to mycophenolic acid: increased resistance to tunicamycin: increased resistance to oleate: decreased resistance to fenpropimorph: decreased resistance to 1,4-dithiothreitol and tacrolimus (anhydrous): increased stress resistance: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	124 total interaction(s) for 107 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 2 Affinity Capture-Western: 3 Biochemical Activity: 2 Two-hybrid: 2
Genetic Interactions	Negative Genetic: 71 Positive Genetic: 37 Synthetic Growth Defect: 2 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:466300 to 468162 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1863 466300..468162 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004706