MTR2/YKL186C Summary Help

Standard Name MTR2 1, 2
Systematic Name YKL186C
Feature Type ORF, Verified
Description mRNA transport regulator; essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA (1)
Name Description Mrna TRansport 2
Chromosomal Location
ChrXI:93298 to 92744 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MTR2 GO evidence and references
  View Computational GO annotations for MTR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 109 genes
Resources
Classical genetics
conditional
reduction of function
Large-scale survey
null
reduction of function
unspecified
Resources
63 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 19
  • Co-crystal Structure: 1
  • Reconstituted Complex: 6
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 5
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 18
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 184
Molecular Weight (Da) 20,783
Isoelectric Point (pI) 7.93
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:93298 to 92744 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
5' UTR intron -167..-14 93465..93312 2011-02-03 2007-04-04
CDS 1..555 93298..92744 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001669
References cited on this page View Complete Literature Guide for MTR2
1) Kadowaki T, et al.  (1994) Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant. Mol Biol Cell 5(11):1253-63
2) Kadowaki T, et al.  (1994) Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J Cell Biol 126(3):649-59