MTF2/YDL044C Summary Help

Standard Name MTF2
Systematic Name YDL044C
Alias NAM1
Feature Type ORF, Verified
Description Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription (1, 2, 3)
Name Description Mitochondrial Transcription Factor 4, 5
Chromosomal Location
ChrIV:375289 to 373967 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -17.93 cM
Gene Ontology Annotations All MTF2 GO evidence and references
  View Computational GO annotations for MTF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
conditional
null
Large-scale survey
null
Resources
23 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 5
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:375289 to 373967 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -17.93 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1323 375289..373967 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002202
References cited on this page View Complete Literature Guide for MTF2
1) Wallis MG, et al.  (1994) The NAM1 protein (NAM1p), which is selectively required for cox1, cytb and atp6 transcript processing/stabilisation, is located in the yeast mitochondrial matrix. Eur J Biochem 222(1):27-32
2) Asher EB, et al.  (1989) Novel class of nuclear genes involved in both mRNA splicing and protein synthesis in Saccharomyces cerevisiae mitochondria. Mol Gen Genet 215(3):517-28
3) Rodeheffer MS, et al.  (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22
4) Lisowsky T  (1990) Molecular analysis of the mitochondrial transcription factor mtf2 of Saccharomyces cerevisiae. Mol Gen Genet 220(2):186-90
5) Lisowsky T and Michaelis G  (1989) Mutations in the genes for mitochondrial RNA polymerase and a second mitochondrial transcription factor of Saccharomyces cerevisiae. Mol Gen Genet 219(1-2):125-8