Standard Name	MTC1 1
Systematic Name	YJL123C
Feature Type	ORF, Verified
Description	Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1 (1, 2, 3, 4)
Name Description	Maintenance of Telomere Capping 1

Chromosomal Location	ChrX:189440 to 188004 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for MTC1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
High-throughput	colocalizes_with COPI-coated vesicle (IDA) cytoplasm (IDA) Golgi apparatus (IDA) colocalizes_with ribosome (IDA)

Large-scale survey
null	competitive fitness: decreased haploproficient protein transport: abnormal resistance to dimethyl sulfoxide: decreased starvation resistance: decreased stress resistance: decreased viable
overexpression	inviable vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	128 total interaction(s) for 81 unique genes/features.
Physical Interactions	Affinity Capture-MS: 13 Affinity Capture-RNA: 1 Biochemical Activity: 1 Two-hybrid: 1
Genetic Interactions	Dosage Growth Defect: 2 Dosage Lethality: 2 Negative Genetic: 70 Phenotypic Enhancement: 16 Phenotypic Suppression: 10 Positive Genetic: 4 Synthetic Growth Defect: 3 Synthetic Lethality: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:189440 to 188004 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1437 189440..188004 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003659