MSS2/YDL107W Summary Help

Standard Name MSS2
Systematic Name YDL107W
Feature Type ORF, Verified
Description Peripherally bound inner membrane protein of the mitochondrial matrix; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p (1, 2, 3)
Name Description Mitochondrial Splicing System
Chromosomal Location
ChrIV:268921 to 269976 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MSS2 GO evidence and references
  View Computational GO annotations for MSS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Large-scale survey
null
overexpression
Resources
58 total interaction(s) for 57 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 47
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 351
Molecular Weight (Da) 41,476
Isoelectric Point (pI) 9.49
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:268921 to 269976 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1056 268921..269976 2004-02-11 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002265
References cited on this page View Complete Literature Guide for MSS2
1) Broadley SA, et al.  (2001) Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiae. Mol Cell Biol 21(22):7663-72
2) Saracco SA and Fox TD  (2002) Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane. Mol Biol Cell 13(4):1122-31
3) Fiumera HL, et al.  (2007) Translocation of mitochondrially synthesized Cox2 domains from the matrix to the intermembrane space. Mol Cell Biol 27(13):4664-73