Standard Name	MSO1
Systematic Name	YNR049C
Feature Type	ORF, Verified
Description	Probable component of the secretory vesicle docking complex; acts at a late step in secretion; shows genetic and physical interactions with Sec1p; required for prospore membrane formation during sporulation; relocalizes from bud neck to nucleus upon DNA replication stress (1, 2, 3, 4)
Name Description	Multicopy suppressor of Sec One 1

Chromosomal Location	ChrXIV:713655 to 713023 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for MSO1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ascospore-type prospore membrane assembly (IMP) cellular membrane fusion (IMP) vesicle docking involved in exocytosis (IDA, IMP, IPI)
Cellular Component
Manually curated	cellular bud membrane (IDA) cellular bud neck (IDA) cellular bud tip (IDA) plasma membrane (IDA) prospore membrane (IDA) SNARE complex (IDA)
High-throughput	cellular bud neck (IDA) cellular bud tip (IDA) cytoplasm (IDA) nucleus (IDA)

Classical genetics
null	endomembrane system morphology: abnormal sporulation: absent
reduction of function	sporulation: delayed
Large-scale survey
null	competitive fitness: increased oxidative stress resistance: decreased resistance to sirolimus: decreased sporulation: absent sporulation efficiency: decreased toxin resistance: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	87 total interaction(s) for 30 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Affinity Capture-Western: 22 PCA: 8 Reconstituted Complex: 4 Two-hybrid: 6
Genetic Interactions	Dosage Lethality: 3 Dosage Rescue: 4 Negative Genetic: 22 Positive Genetic: 1 Synthetic Growth Defect: 4 Synthetic Lethality: 10 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:713655 to 713023 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..633 713655..713023 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005332