MRPL44/YMR225C Summary Help

Standard Name MRPL44 1
Systematic Name YMR225C
Alias YMR44 2
Feature Type ORF, Verified
Description Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress (3, 4)
Name Description Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias YmL44 1
Chromosomal Location
ChrXIII:721403 to 720960 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 158 cM
Gene Ontology Annotations All MRPL44 GO evidence and references
  View Computational GO annotations for MRPL44
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
Resources
15 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 4

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 98
Molecular Weight (Da) 11,476
Isoelectric Point (pI) 10.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:721403 to 720960 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 158 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..58 721403..721346 2011-02-03 1996-07-31
Intron 59..205 721345..721199 2011-02-03 1996-07-31
CDS 206..444 721198..720960 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004838
References cited on this page View Complete Literature Guide for MRPL44
1) Kitakawa M, et al.  (1997) Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Eur J Biochem 245(2):449-56
2) Matsushita Y, et al.  (1989) Cloning and analysis of the nuclear genes for two mitochondrial ribosomal proteins in yeast. Mol Gen Genet 219(1-2):119-24
3) Graack HR and Wittmann-Liebold B  (1998) Mitochondrial ribosomal proteins (MRPs) of yeast. Biochem J 329 ( Pt 3)():433-48
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76