MRPL4/YLR439W Summary Help

Standard Name MRPL4 1
Systematic Name YLR439W
Feature Type ORF, Verified
Description Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit (1, 2)
Name Description Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias YmL4 1
Chromosomal Location
ChrXII:1014491 to 1015450 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MRPL4 GO evidence and references
  View Computational GO annotations for MRPL4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
65 total interaction(s) for 45 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 55
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 319
Molecular Weight (Da) 36,965
Isoelectric Point (pI) 7.69
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:1014491 to 1015450 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..960 1014491..1015450 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004431
References cited on this page View Complete Literature Guide for MRPL4
1) Graack HR, et al.  (1995) Gene MRP-L4, encoding mitochondrial ribosomal protein YmL4, is indispensable for proper non-respiratory cell functions in yeast. Gene 152(1):107-12
2) Gruschke S, et al.  (2010) Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem 285(25):19022-8