Standard Name	MRPL10 1
Systematic Name	YNL284C
Alias	MRPL18
Feature Type	ORF, Verified
Description	Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels (1, 2)
Name Description	Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias	YmL10 1 , YmL18 1

Chromosomal Location	ChrXIV:104102 to 103134 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for MRPL10
Molecular Function
Manually curated	structural constituent of ribosome (IDA)
Biological Process
Manually curated	mitochondrial translation (IC)
Cellular Component
Manually curated	mitochondrial large ribosomal subunit (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	chronological lifespan: decreased
Large-scale survey
null	cell size: decreased competitive fitness: decreased dessication resistance: decreased endocytosis: decreased heat sensitivity: increased metal resistance: increased metal resistance: decreased resistance to 2,4-dichlorophenol: decreased resistance to 4-chlorophenol: decreased resistance to farnesol: decreased resistance to trichothecene: increased respiratory growth: decreased rate respiratory growth: absent stress resistance: increased utilization of carbon source: decreased vacuolar morphology: abnormal vegetative growth: absent
overexpression	filamentous growth: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	84 total interaction(s) for 47 unique genes/features.
Physical Interactions	Affinity Capture-MS: 77 Affinity Capture-RNA: 2
Genetic Interactions	Negative Genetic: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:104102 to 103134 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..969 104102..103134 2005-11-07 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005228