MRH1/YDR033W Summary Help

Standard Name MRH1 1
Systematic Name YDR033W
Feature Type ORF, Verified
Description Protein that localizes primarily to the plasma membrane; also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; MRH1 has a paralog, YRO2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Membrane protein Related to Hsp30p 1
Chromosomal Location
ChrIV:508147 to 509109 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MRH1 GO evidence and references
  View Computational GO annotations for MRH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
84 total interaction(s) for 65 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 7
  • Co-fractionation: 3
  • PCA: 1
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 53
  • Positive Genetic: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 320
Molecular Weight (Da) 36,190
Isoelectric Point (pI) 9.85
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:508147 to 509109 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..963 508147..509109 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000002440
References cited on this page View Complete Literature Guide for MRH1
1) Wu K, et al.  (2000) Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae. Biochim Biophys Acta 1463(2):477-82
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
4) Reinders J, et al.  (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906