MPC54/YOR177C Summary Help

Standard Name MPC54
Systematic Name YOR177C
Feature Type ORF, Verified
Description Component of the meiotic outer plaque; a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate (1, 2, 3)
Name Description Meiotic Plaque Component
Chromosomal Location
ChrXV:667179 to 665785 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MPC54 GO evidence and references
  View Computational GO annotations for MPC54
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
36 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 1
  • Biochemical Activity: 7
  • FRET: 4
  • Reconstituted Complex: 3
  • Two-hybrid: 11

Genetic Interactions
  • Negative Genetic: 3
  • Phenotypic Enhancement: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 464
Molecular Weight (Da) 54,358
Isoelectric Point (pI) 7.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:667179 to 665785 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1395 667179..665785 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005703
References cited on this page View Complete Literature Guide for MPC54
1) Knop M and Strasser K  (2000) Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis. EMBO J 19(14):3657-67
2) Nickas ME, et al.  (2003) Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Eukaryot Cell 2(3):431-45
3) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64