Standard Name	MOG1
Systematic Name	YJR074W
Feature Type	ORF, Verified
Description	Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p (1, 2, 3)
Name Description	Multicopy suppressor Of ts Gsp1 1

Chromosomal Location	ChrX:573095 to 573751 | ORF Map | GBrowse

	View Computational GO annotations for MOG1
Molecular Function
Manually curated	Ran GTPase binding (IPI)
Biological Process
Manually curated	protein import into nucleus (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Classical genetics
null	20S pre-rRNA accumulation: increased tellurium atom accumulation: increased metal resistance: decreased metal resistance: increased vegetative growth: decreased rate
overexpression	silencing: decreased
Large-scale survey
null	cell size: increased competitive fitness: decreased dessication resistance: decreased heat sensitivity: increased hyperosmotic stress resistance: decreased lipid particle morphology: abnormal metal resistance: decreased oxidative stress resistance: decreased resistance to bleomycin: increased resistance to quinine: increased resistance to wortmannin: increased resistance to cycloheximide: decreased resistance to camptothecin: increased resistance to fenpropimorph: increased resistance to fluconazole: increased resistance to sirolimus: decreased resistance to oleate: decreased resistance to ethanol: decreased resistance to 5-fluorouracil: decreased resistance to tirapazamine: decreased resistance to sulfometuron methyl: decreased resistance to wortmannin: decreased resistance to propolis extract: decreased resistance to hydroxyurea: decreased resistance to tunicamycin: decreased resistance to cycloheximide: increased resistance to benomyl: decreased respiratory growth: decreased rate sporulation: abnormal utilization of carbon source: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	204 total interaction(s) for 180 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 2 Affinity Capture-Western: 2 Co-purification: 1 Reconstituted Complex: 4 Two-hybrid: 7
Genetic Interactions	Dosage Rescue: 6 Negative Genetic: 122 Phenotypic Suppression: 1 Positive Genetic: 41 Synthetic Growth Defect: 9 Synthetic Lethality: 7
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:573095 to 573751 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..657 573095..573751 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003835