Standard Name	MOB2 1
Systematic Name	YFL034C-B
Alias	YFL035C , YFL035C-A
Feature Type	ORF, Verified
Description	Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p (2, 3, 4)
Name Description	Mps One Binder 1

Chromosomal Location	ChrVI:63993 to 63016 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for MOB2
Molecular Function
Manually curated	protein kinase activator activity (IDA)
Biological Process
Manually curated	budding cell apical bud growth (IGI, IMP) cytokinetic cell separation (IMP) establishment or maintenance of cell polarity (IMP) positive regulation of protein phosphorylation (IMP)
Cellular Component
Manually curated	cellular bud (IDA) cellular bud neck (IDA) cellular bud tip (IDA) mating projection tip (IDA) nucleus (IDA)

Classical genetics
null	CTS1 mRNA accumulation: decreased actin cytoskeleton morphology: abnormal axial budding pattern: decreased bipolar budding pattern: decreased cell shape: abnormal colony appearance: abnormal liquid culture appearance: abnormal mating projection morphology: abnormal YFP-Ace2p distribution: abnormal Cbk1p-GFP distribution: abnormal
Large-scale survey
conditional	resistance to hydroxyurea: decreased resistance to methyl methanesulfonate: decreased
null	haploproficient inviable
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	45 total interaction(s) for 30 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 4 Reconstituted Complex: 1 Two-hybrid: 7
Genetic Interactions	Dosage Rescue: 9 Negative Genetic: 3 Phenotypic Enhancement: 2 Phenotypic Suppression: 1 Positive Genetic: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 8 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:63993 to 63016 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..20 63993..63974 2011-02-03 1996-07-31 Intron 21..134 63973..63860 2011-02-03 1996-07-31 CDS 135..978 63859..63016 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (21 - 134)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001859