MNR2/YKL064W Summary Help

Standard Name MNR2 1
Systematic Name YKL064W
Feature Type ORF, Verified
Description Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations (1, 2)
Name Description MaNganese Resistance 1
Chromosomal Location
ChrXI:317764 to 320673 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MNR2 GO evidence and references
  View Computational GO annotations for MNR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
34 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 9
  • PCA: 2

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 1
  • Negative Genetic: 6
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 969
Molecular Weight (Da) 109,735
Isoelectric Point (pI) 7.56
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:317764 to 320673 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2910 317764..320673 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001547
References cited on this page View Complete Literature Guide for MNR2
1) MacDiarmid CW and Gardner RC  (1998) Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion. J Biol Chem 273(3):1727-32
2) Pisat NP, et al.  (2009) MNR2 regulates intracellular magnesium storage in Saccharomyces cerevisiae. Genetics 183(3):873-84