MNN2/YBR015C Summary Help

Standard Name MNN2 1
Systematic Name YBR015C
Alias TTP1 , CRV4 , LDB8
Feature Type ORF, Verified
Description Alpha-1,2-mannosyltransferase; responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment (2)
Name Description MaNNosyltransferase
Chromosomal Location
ChrII:269503 to 267710 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MNN2 GO evidence and references
  View Computational GO annotations for MNN2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
overexpression
Resources
156 total interaction(s) for 112 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-Western: 2
  • Co-purification: 3
  • PCA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 96
  • Phenotypic Enhancement: 24
  • Phenotypic Suppression: 8
  • Positive Genetic: 5
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 597
Molecular Weight (Da) 67,773
Isoelectric Point (pI) 6.18
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:269503 to 267710 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1794 269503..267710 2004-07-16 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000219
References cited on this page View Complete Literature Guide for MNN2
1) Raschke WC, et al.  (1973) Genetic control of yeast mannan structure. Isolation and characterization of mannan mutants. J Biol Chem 248(13):4660-6
2) Rayner JC and Munro S  (1998) Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae. J Biol Chem 273(41):26836-43