MIS1/YBR084W Summary Help

Standard Name MIS1 1
Systematic Name YBR084W
Feature Type ORF, Verified
Description Mitochondrial C1-tetrahydrofolate synthase; involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase (1)
Name Description MItochondrial C1-tetrahydrofolate Synthase 1
Chromosomal Location
ChrII:411054 to 413981 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MIS1 GO evidence and references
  View Computational GO annotations for MIS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
repressible
Resources
110 total interaction(s) for 95 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 63
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1

Genetic Interactions
  • Negative Genetic: 37
  • Phenotypic Enhancement: 2
  • Positive Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 975
Molecular Weight (Da) 106,216
Isoelectric Point (pI) 9.16
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:411054 to 413981 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2928 411054..413981 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000288
References cited on this page View Complete Literature Guide for MIS1
1) Shannon KW and Rabinowitz JC  (1988) Isolation and characterization of the Saccharomyces cerevisiae MIS1 gene encoding mitochondrial C1-tetrahydrofolate synthase. J Biol Chem 263(16):7717-25