MIX17/YMR002W Summary Help

Standard Name MIX17 1
Systematic Name YMR002W
Alias MIC17 2
Feature Type ORF, Verified
Description Mitochondrial intermembrane space protein; required for normal oxygen consumption; contains twin cysteine-x9-cysteine motifs; protein abundance increases in response to DNA replication stress (2, 3, 4)
Name Description Mitochondrial Intermembrane space CX(n)C motif protein 1
Chromosomal Location
ChrXIII:272193 to 272663 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MIX17 GO evidence and references
  View Computational GO annotations for MIX17
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
13 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • PCA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 156
Molecular Weight (Da) 16,669
Isoelectric Point (pI) 8.53
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:272193 to 272663 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..471 272193..272663 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004604
References cited on this page View Complete Literature Guide for MIX17
1) Pfanner N, et al.  (2014) Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol 204(7):1083-6
2) Gabriel K, et al.  (2007) Novel Mitochondrial Intermembrane Space Proteins as Substrates of the MIA Import Pathway. J Mol Biol 365(3):612-620
3) Longen S, et al.  (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76