MHP1/YJL042W Summary Help

Standard Name MHP1 1
Systematic Name YJL042W
Feature Type ORF, Verified
Description Microtubule-associated protein involved in microtubule organization; involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins (1, 2)
Name Description MAP-Homologous Protein 1
Chromosomal Location
ChrX:361249 to 365445 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MHP1 GO evidence and references
  View Computational GO annotations for MHP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 17 genes
Resources
Large-scale survey
null
overexpression
Resources
91 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 2
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 62
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 4
  • Positive Genetic: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,398
Molecular Weight (Da) 155,206
Isoelectric Point (pI) 7.28
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:361249 to 365445 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4197 361249..365445 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003578
References cited on this page View Complete Literature Guide for MHP1
1) Irminger-Finger I, et al.  (1996) MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function. J Cell Biol 135(5):1323-39
2) Irminger-Finger I and Mathis N  (1998) Effect of microtubule-associated protein MHP1 on microtubule assembly and cell cycle progression in Saccharomyces cerevisiae. Cell Struct Funct 23(4):209-19