MFA2/YNL145W Summary Help

Standard Name MFA2 1
Systematic Name YNL145W
Feature Type ORF, Verified
Description Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1 (2, 3)
Name Description Mating Factor A
Chromosomal Location
ChrXIV:352414 to 352530 | ORF Map | GBrowse
Gbrowse
Genetic position: -107.4 cM
Gene Ontology Annotations All MFA2 GO evidence and references
  View Computational GO annotations for MFA2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
69 total interaction(s) for 63 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 10
  • Biochemical Activity: 1
  • Co-purification: 1
  • Protein-RNA: 8

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 47
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 38
Molecular Weight (Da) 4,229
Isoelectric Point (pI) 8.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:352414 to 352530 | ORF Map | GBrowse
SGD ORF map
Genetic position: -107.4 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..117 352414..352530 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005089
References cited on this page View Complete Literature Guide for MFA2
1) Michaelis, S.  (1993) Personal Communication, Mortimer Map Edition 12
2) Chen P, et al.  (1997) Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor. J Cell Biol 136(2):251-69
3) Michaelis S and Herskowitz I  (1988) The a-factor pheromone of Saccharomyces cerevisiae is essential for mating. Mol Cell Biol 8(3):1309-18