MDM31/YHR194W Summary Help

Standard Name MDM31 1
Systematic Name YHR194W
Feature Type ORF, Verified
Description Mitochondrial protein that may have a role in phospholipid metabolism; inner membrane protein with similarity to Mdm32p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MMM2, MDM10, MDM12, and MDM34 (2, 3)
Name Description Mitochondrial Distribution and Morphology 1
Chromosomal Location
ChrVIII:488657 to 490396 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MDM31 GO evidence and references
  View Computational GO annotations for MDM31
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
63 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 2
  • PCA: 1

Genetic Interactions
  • Dosage Rescue: 6
  • Negative Genetic: 26
  • Phenotypic Enhancement: 2
  • Positive Genetic: 7
  • Synthetic Growth Defect: 9
  • Synthetic Lethality: 10

Resources
Expression Summary
histogram
Resources
Length (a.a.) 579
Molecular Weight (Da) 66,702
Isoelectric Point (pI) 10.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:488657 to 490396 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1740 488657..490396 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001237
References cited on this page View Complete Literature Guide for MDM31
1) Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
2) Dimmer KS, et al.  (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15
3) Tamura Y, et al.  (2012) Role for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking. J Biol Chem 287(19):15205-18