MCP1/YOR228C Summary Help

Standard Name MCP1 1
Systematic Name YOR228C
Feature Type ORF, Verified
Description Mitochondrial protein of unknown function involved in lipid homeostasis; integral membrane protein that localizes to the mitochondrial outer membrane; involved in mitochondrial morphology; interacts genetically with MDM10, and other members of the ERMES complex; contains five predicted transmembrane domains (1, 2)
Name Description Mdm10 Complementing Protein 1
Chromosomal Location
ChrXV:767777 to 766869 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MCP1 GO evidence and references
  View Computational GO annotations for MCP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Large-scale survey
null
overexpression
Resources
92 total interaction(s) for 75 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1

Genetic Interactions
  • Negative Genetic: 83
  • Positive Genetic: 6
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 302
Molecular Weight (Da) 33,989
Isoelectric Point (pI) 10.76
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:767777 to 766869 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..909 767777..766869 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005754
References cited on this page View Complete Literature Guide for MCP1
1) Tan T, et al.  (2013) Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis. J Cell Sci 126(Pt 16):3563-74
2) Zahedi RP, et al.  (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 17(3):1436-50