MAS2/YHR024C Summary Help

Standard Name MAS2 1
Systematic Name YHR024C
Alias MIF2
Feature Type ORF, Verified
Description Larger subunit of the mitochondrial processing protease (MPP); essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins (2, 3)
Name Description Mitochondrial ASsembly 1
Gene Product Alias mitochondrial processing protease alpha subunit 2
Chromosomal Location
ChrVIII:159192 to 157744 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 26 cM
Gene Ontology Annotations All MAS2 GO evidence and references
  View Computational GO annotations for MAS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
conditional
Large-scale survey
null
overexpression
unspecified
Resources
16 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-RNA: 1
  • Co-purification: 1

Genetic Interactions
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 482
Molecular Weight (Da) 53,337
Isoelectric Point (pI) 6.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:159192 to 157744 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 26 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1449 159192..157744 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001066
References cited on this page View Complete Literature Guide for MAS2
1) Yaffe MP and Schatz G  (1984) Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A 81(15):4819-23
2) Jensen RE and Yaffe MP  (1988) Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit. EMBO J 7(12):3863-71
3) Yang M, et al.  (1988) Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes. EMBO J 7(12):3857-62