MAS1/YLR163C Summary Help

Standard Name MAS1 1
Systematic Name YLR163C
Alias MIF1
Feature Type ORF, Verified
Description Smaller subunit of the mitochondrial processing protease (MPP); essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins (2, 3)
Name Description Mitochondrial ASsembly 1
Gene Product Alias mitochondrial processing protease beta subunit 2
Chromosomal Location
ChrXII:493254 to 491866 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MAS1 GO evidence and references
  View Computational GO annotations for MAS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
repressible
Resources
27 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 4
  • Co-purification: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 462
Molecular Weight (Da) 51,083
Isoelectric Point (pI) 7.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:493254 to 491866 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): YLR163W-A
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1389 493254..491866 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004153
References cited on this page View Complete Literature Guide for MAS1
1) Yaffe MP and Schatz G  (1984) Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A 81(15):4819-23
2) Witte C, et al.  (1988) MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease. EMBO J 7(5):1439-47
3) Yang M, et al.  (1988) Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes. EMBO J 7(12):3857-62