MAP2/YBL091C Summary

MAP2 BASIC INFORMATION

Standard Name	MAP2
Systematic Name	YBL091C
Feature Type	ORF, Verified
Description	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p (1, 2)
Name Description	Methionine AminoPeptidase 1

GO Annotations	All MAP2 GO evidence and references
	View Computational GO annotations for MAP2
Molecular Function
Manually curated	metalloaminopeptidase activity (IGI, ISA)
Biological Process
Manually curated	proteolysis (IDA)
Cellular Component
Manually curated	cytoplasm (TAS)

Mutant Phenotype	All MAP2 Phenotype details and references
Large-scale survey
null	viable

Interactions	MAP2 All interactions details and references
	5 total interaction(s) for 4 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Two-hybrid: 1
Genetic Interactions	Phenotypic Suppression: 1 Synthetic Lethality: 1

Sequence Information

ChrII:48625 to 47360 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-01-29 | Sequence: 1997-07-27

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1266	48625..47360	2004-01-29	1997-07-27

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000187

MAP2 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MAP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MAP2]

1)	Li X and Chang YH (1995) Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases. Proc Natl Acad Sci U S A 92(26):12357-61
2)	Vetro JA, et al. (2005) Evidence of a dominant negative mutant of yeast methionine aminopeptidase type 2 in Saccharomyces cerevisiae. J Cell Biochem 94(4):656-68

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