MAP1/YLR244C Summary Help

Standard Name MAP1
Systematic Name YLR244C
Feature Type ORF, Verified
Description Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p (1, 2, 3)
Name Description Methionine AminoPeptidase
Chromosomal Location
ChrXII:626331 to 625168 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MAP1 GO evidence and references
  View Computational GO annotations for MAP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
26 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 3
  • PCA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 3

Genetic Interactions
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 387
Molecular Weight (Da) 43,373
Isoelectric Point (pI) 7.82
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:626331 to 625168 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1164 626331..625168 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004234
References cited on this page View Complete Literature Guide for MAP1
1) Li X and Chang YH  (1995) Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases. Proc Natl Acad Sci U S A 92(26):12357-61
2) Chang YH, et al.  (1992) Molecular cloning, sequencing, deletion, and overexpression of a methionine aminopeptidase gene from Saccharomyces cerevisiae. J Biol Chem 267(12):8007-11
3) Chang YH, et al.  (1990) Purification and characterization of a methionine aminopeptidase from Saccharomyces cerevisiae. J Biol Chem 265(32):19892-7