Standard Name	MAP1
Systematic Name	YLR244C
Feature Type	ORF, Verified
Description	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p (1, 2, 3)
Name Description	Methionine AminoPeptidase

Chromosomal Location	ChrXII:626331 to 625168 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for MAP1
Molecular Function
Manually curated	metalloaminopeptidase activity (IDA) mRNA binding (IDA)
Biological Process
Manually curated	negative regulation of gene expression (IMP) protein initiator methionine removal involved in protein maturation (IMP)
Cellular Component
Manually curated	cytosolic ribosome (IDA)

Classical genetics
null	replicative lifespan: decreased resistance to 1,1'-azobis(N,N-dimethylformamide): decreased
Large-scale survey
null	acid pH resistance: decreased alkaline pH resistance: decreased budding pattern: abnormal cell shape: abnormal cell size: decreased competitive fitness: decreased dessication resistance: decreased heat sensitivity: increased hyperosmotic stress resistance: decreased metal resistance: decreased resistance to dimethyl sulfoxide: decreased resistance to CTBT: decreased resistance to amitrole: decreased resistance to cycloheximide: decreased resistance to hydroxyurea: decreased resistance to wortmannin: decreased resistance to sirolimus: increased resistance to L-1,4-dithiothreitol: decreased resistance to benomyl: decreased resistance to benzo[a]pyrene: decreased resistance to hygromycin B: decreased resistance to caffeine: decreased utilization of phosphorus source: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	24 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Affinity Capture-RNA: 2 Biochemical Activity: 3 PCA: 1 Reconstituted Complex: 1 Two-hybrid: 3
Genetic Interactions	Phenotypic Suppression: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 1 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:626331 to 625168 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1164 626331..625168 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004234