Standard Name	MAG1
Systematic Name	YER142C
Alias	MMS5 1
Feature Type	ORF, Verified
Description	3-methyl-adenine DNA glycosylase; involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired; protein abundance increases in response to DNA replication stress (2, 3)
Name Description	3-MethylAdenine DNA Glycosylase 2

Chromosomal Location	ChrV:456036 to 455146 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 110 cM

	View Computational GO annotations for MAG1
Molecular Function
Manually curated	alkylbase DNA N-glycosylase activity (IDA)
Biological Process
Manually curated	base-excision repair, AP site formation (IGI, IMP) DNA dealkylation involved in DNA repair (IEP, IGI, ISS)
Cellular Component
Manually curated	nucleus (IC)

Classical genetics
null	resistance to methyl methanesulfonate: decreased
reduction of function	UV resistance: normal X ray resistance: normal resistance to methyl methanesulfonate: decreased
Large-scale survey
null	competitive fitness: increased haploinsufficient resistance to amitrole: decreased resistance to cycloheximide: decreased resistance to methyl methanesulfonate: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	88 total interaction(s) for 71 unique genes/features.
Physical Interactions	Affinity Capture-MS: 17 Biochemical Activity: 1 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 26 Phenotypic Enhancement: 23 Phenotypic Suppression: 6 Positive Genetic: 5 Synthetic Growth Defect: 3 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:456036 to 455146 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 110 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..891 456036..455146 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000944