LYS14/YDR034C Summary

LYS14 BASIC INFORMATION

Standard Name	LYS14 1
Systematic Name	YDR034C
Feature Type	ORF, Verified
Description	Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer (2)
Name Description	LYSine requiring

GO Annotations	All LYS14 GO evidence and references
	View Computational GO annotations for LYS14
Molecular Function
Manually curated	transcription activator activity (IMP, TAS)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	lysine biosynthetic process via aminoadipic acid (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Regulatory Role
Regulatory modules	predicted: cellcycle ( 263 )

Mutant Phenotype	All LYS14 Phenotype details and references
Large-scale survey
null	competitive fitness: decreased resistance to selenomethionine: increased viable

Interactions	LYS14 All interactions details and references
	4 total interaction(s) for 4 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Two-hybrid: 2

Sequence Information

ChrIV:512107 to 509735 | |

Note: this feature is encoded on the Crick strand.

Genetic position: 8 cM

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2373	512107..509735	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002441

LYS14 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for LYS14

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for LYS14]

1)	Contopoulou, C.R. (1989) Personal Communication, Mortimer Map Edition 10
2)	Feller A, et al. (1994) Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation. Mol Cell Biol 14(10):6411-8

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