LSB5/YCL034W Summary Help

Standard Name LSB5 1
Systematic Name YCL034W
Feature Type ORF, Verified
Description Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; may mediate disassembly of the Pan1 complex from the endocytic coat (1, 2)
Name Description Las Seventeen Binding protein 1
Chromosomal Location
ChrIII:61658 to 62722 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All LSB5 GO evidence and references
  View Computational GO annotations for LSB5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Large-scale survey
null
Resources
20 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 2
  • Reconstituted Complex: 1
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 1
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 354
Molecular Weight (Da) 39,872
Isoelectric Point (pI) 5.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:61658 to 62722 | ORF Map | GBrowse
This feature contains embedded feature(s): YCLX05C
SGD ORF map
Last Update Coordinates: 2000-09-13 | Sequence: 2000-09-13
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1065 61658..62722 2000-09-13 2000-09-13
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000539
References cited on this page View Complete Literature Guide for LSB5
1) Madania A, et al.  (1999) The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex. Mol Biol Cell 10(10):3521-38
2) Toret CP, et al.  (2008) Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking. Traffic 9(5):848-59