LPP1/YDR503C Summary Help

Standard Name LPP1 1
Systematic Name YDR503C
Feature Type ORF, Verified
Description Lipid phosphate phosphatase; catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA (1, 2)
Name Description Lipid Phosphate Phosphatase 1
Chromosomal Location
ChrIV:1455866 to 1455042 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All LPP1 GO evidence and references
  View Computational GO annotations for LPP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Large-scale survey
null
overexpression
Resources
41 total interaction(s) for 33 unique genes/features.
Physical Interactions
  • Co-purification: 1
  • PCA: 5
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Negative Genetic: 20
  • Phenotypic Enhancement: 1
  • Positive Genetic: 10
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 274
Molecular Weight (Da) 31,586
Isoelectric Point (pI) 8.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1455866 to 1455042 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..825 1455866..1455042 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002911
References cited on this page View Complete Literature Guide for LPP1
1) Toke DA, et al.  (1998) Isolation and characterization of the Saccharomyces cerevisiae LPP1 gene encoding a Mg2+-independent phosphatidate phosphatase. J Biol Chem 273(23):14331-8
2) Furneisen JM and Carman GM  (2000) Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae. Biochim Biophys Acta 1484(1):71-82