LOT5/YKL183W Summary Help

Standard Name LOT5 1
Systematic Name YKL183W
Feature Type ORF, Verified
Description Protein of unknown function; gene expression increases in cultures shifted to a lower temperature; protein abundance increases in response to DNA replication stress (1, 2)
Name Description LOw Temperature-responsive 1
Chromosomal Location
ChrXI:98721 to 99641 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All LOT5 GO evidence and references
  View Computational GO annotations for LOT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 61 genes
Resources
Large-scale survey
null
overexpression
Resources
16 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 7
  • Positive Genetic: 4
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 306
Molecular Weight (Da) 34,326
Isoelectric Point (pI) 4.3
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:98721 to 99641 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..921 98721..99641 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001666
References cited on this page View Complete Literature Guide for LOT5
1) Zhang L, et al.  (2001) Multiple mechanisms regulate expression of low temperature responsive (LOT) genes in Saccharomyces cerevisiae. Biochem Biophys Res Commun 283(2):531-5
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76