LGE1/YPL055C Summary Help

Standard Name LGE1 1
Systematic Name YPL055C
Feature Type ORF, Verified
Description Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division (1, 2)
Name Description LarGE cells 1
Chromosomal Location
ChrXVI:454990 to 453992 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All LGE1 GO evidence and references
  View Computational GO annotations for LGE1
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
High-throughput
Regulators 11 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
838 total interaction(s) for 458 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 56
  • Affinity Capture-RNA: 2
  • Co-localization: 1
  • PCA: 1
  • Two-hybrid: 13

Genetic Interactions
  • Negative Genetic: 405
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 1
  • Positive Genetic: 74
  • Synthetic Growth Defect: 169
  • Synthetic Lethality: 103
  • Synthetic Rescue: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 332
Molecular Weight (Da) 37,309
Isoelectric Point (pI) 10.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:454990 to 453992 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..999 454990..453992 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005976
References cited on this page View Complete Literature Guide for LGE1
1) Jorgensen P, et al.  (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400
2) Jordan PW, et al.  (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222