KTR2/YKR061W Summary Help

Standard Name KTR2 1
Systematic Name YKR061W
Feature Type ORF, Verified
Description Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR2 has a paralog, YUR1, that arose from the whole genome duplication (2, 3)
Name Description Kre Two Related 4
Chromosomal Location
ChrXI:557677 to 558954 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All KTR2 GO evidence and references
  View Computational GO annotations for KTR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Large-scale survey
null
overexpression
Resources
25 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Positive Genetic: 1
  • Synthetic Growth Defect: 10
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 425
Molecular Weight (Da) 50,651
Isoelectric Point (pI) 5.61
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:557677 to 558954 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1278 557677..558954 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001769
References cited on this page View Complete Literature Guide for KTR2
1) Bussey, H.  (1992) Personal Communication, Mortimer Map Edition 11
2) Lussier M, et al.  (1996) Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem 271(18):11001-8
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Lussier M, et al.  (1997) Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism. Yeast 13(3):267-74