Standard Name	KRE1 1
Systematic Name	YNL322C
Feature Type	ORF, Verified
Description	Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor (2)
Name Description	Killer toxin REsistant 3

Chromosomal Location	ChrXIV:34235 to 33294 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -235 cM

	View Computational GO annotations for KRE1
Molecular Function
Manually curated	structural constituent of cell wall (TAS)
Biological Process
Manually curated	fungal-type cell wall organization (TAS)
Cellular Component
Manually curated	fungal-type cell wall (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	(1->6)-beta-D-glucan accumulation: decreased dessication resistance: decreased
reduction of function	killer toxin resistance: increased
Large-scale survey
null	alkaline pH resistance: decreased auxotrophy polyphosphate accumulation: abnormal competitive fitness: decreased dessication resistance: decreased resistance to methyl methanesulfonate: increased resistance to camptothecin: increased resistance to bleomycin: increased resistance to cycloheximide: decreased resistance to streptomycin: decreased resistance to sirolimus: increased resistance to cyclosporin A: decreased resistance to FK506: decreased resistance to tunicamycin: decreased resistance to hydrogen chloride: decreased resistance to quinine: decreased resistance to neothyonidioside: decreased resistance to fenpropimorph: decreased resistance to fluconazole: decreased resistance to chloroquine: decreased resistance to caffeine: increased resistance to calcium dichloride: decreased resistance to hygromycin B: decreased resistance to benzo[a]pyrene: decreased stress resistance: decreased vegetative growth: decreased rate viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	189 total interaction(s) for 131 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 2 PCA: 1 Protein-RNA: 1
Genetic Interactions	Negative Genetic: 44 Phenotypic Enhancement: 20 Phenotypic Suppression: 1 Positive Genetic: 6 Synthetic Growth Defect: 77 Synthetic Lethality: 35 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:34235 to 33294 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -235 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..942 34235..33294 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005266