Standard Name	KIP1 1
Systematic Name	YBL063W
Alias	CIN9
Feature Type	ORF, Verified
Description	Kinesin-related motor protein required for mitotic spindle assembly, chromosome segregation, and 2 micron plasmid partitioning; functionally redundant with Cin8p for chromosomal but not plasmid functions (1, 2, 3)
Name Description	KInesin related Protein 1

Chromosomal Location	ChrII:101886 to 105221 | ORF Map | GBrowse

	View Computational GO annotations for KIP1
Molecular Function
Manually curated	microtubule motor activity (TAS) structural constituent of cytoskeleton (IPI)
Biological Process
Manually curated	microtubule depolymerization (IMP) mitotic anaphase B (IMP) mitotic sister chromatid segregation (IGI) plasmid partitioning (IMP) spindle pole body separation (IGI)
Cellular Component
Manually curated	kinesin complex (TAS) spindle microtubule (IDA) spindle pole body (IDA)
High-throughput	nucleus (IDA)

Classical genetics
null	cell cycle progression in anaphase: increased duration chromosome/plasmid maintenance: abnormal spindle morphology: abnormal
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to L-canavanine: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	60 total interaction(s) for 44 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Biochemical Activity: 1 Co-purification: 1 Two-hybrid: 12
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 2 Negative Genetic: 10 Phenotypic Enhancement: 6 Phenotypic Suppression: 8 Positive Genetic: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 10 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:101886 to 105221 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..3336 101886..105221 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000159