KIP1/YBL063W Summary Help

Standard Name KIP1 1
Systematic Name YBL063W
Alias CIN9 2
Feature Type ORF, Verified
Description Kinesin-related motor protein; required for mitotic spindle assembly, chromosome segregation, and 2 micron plasmid partitioning; functionally redundant with Cin8p for chromosomal but not plasmid functions (1, 2, 3)
Name Description KInesin related Protein 1
Chromosomal Location
ChrII:101886 to 105221 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All KIP1 GO evidence and references
  View Computational GO annotations for KIP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
60 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • Two-hybrid: 12

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 2
  • Negative Genetic: 10
  • Phenotypic Enhancement: 6
  • Phenotypic Suppression: 8
  • Positive Genetic: 2
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 10
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,111
Molecular Weight (Da) 125,793
Isoelectric Point (pI) 6.85
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:101886 to 105221 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3336 101886..105221 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000159
References cited on this page View Complete Literature Guide for KIP1
1) Roof DM, et al.  (1992) Kinesin-related proteins required for assembly of the mitotic spindle. J Cell Biol 118(1):95-108
2) Hoyt MA, et al.  (1992) Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J Cell Biol 118(1):109-20
3) Cui H, et al.  (2009) The selfish yeast plasmid uses the nuclear motor Kip1p but not Cin8p for its localization and equal segregation. J Cell Biol 185(2):251-64