KGD1/YIL125W Summary Help

Standard Name KGD1 1
Systematic Name YIL125W
Alias OGD1
Feature Type ORF, Verified
Description Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA (2)
Name Description alpha-KetoGlutarate Dehydrogenase
Chromosomal Location
ChrIX:122689 to 125733 | ORF Map | GBrowse
Gbrowse
Genetic position: -91 cM
Gene Ontology Annotations All KGD1 GO evidence and references
  View Computational GO annotations for KGD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
62 total interaction(s) for 47 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 43
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 2
  • Phenotypic Suppression: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,014
Molecular Weight (Da) 114,415
Isoelectric Point (pI) 7.21
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:122689 to 125733 | ORF Map | GBrowse
SGD ORF map
Genetic position: -91 cM
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3045 122689..125733 1994-12-10 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001387
References cited on this page View Complete Literature Guide for KGD1
1) Subik, J.  (1992) Personal Communication, Mortimer Map Edition 11
2) Repetto B and Tzagoloff A  (1989) Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase. Mol Cell Biol 9(6):2695-705