Standard Name	KEG1 1
Systematic Name	YFR042W
Feature Type	ORF, Verified
Description	Integral membrane protein of the ER; physically interacts with Kre6p; has a role in the synthesis of beta-1,6-glucan in the cell wall; required for cell viability (1, 2)
Name Description	Kre6-binding ER protein responsible for Glucan synthesis 1

Chromosomal Location	ChrVI:238458 to 239060 | ORF Map | GBrowse

	View Computational GO annotations for KEG1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	(1->6)-beta-D-glucan biosynthetic process (IMP) chromosome organization (IMP)
Cellular Component
Manually curated	integral to endoplasmic reticulum membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
conditional	(1->6)-beta-D-glucan accumulation: decreased chromosome/plasmid maintenance: abnormal colony sectoring: increased killer toxin resistance: decreased resistance to calcofluor white: decreased resistance to enzymatic treatment: decreased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable starvation resistance: decreased
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 14 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Affinity Capture-Western: 5 Two-hybrid: 4
Genetic Interactions	Dosage Rescue: 2 Phenotypic Suppression: 3 Synthetic Growth Defect: 3 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:238458 to 239060 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..603 238458..239060 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001938