Search results for Locus Summary pages at SGD

Your query, K2, returned 42 hits to the following gene names:

Match Gene Name Systematic Name Alias(es) Position Info Description
ADK2 ADK2 YER170W AKY3, PAK3, adenylate kinase ADK2

ChrV:525974 to 526651 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..678 525974..526651

Genetic position: 146 cM

Mitochondrial adenylate kinase; catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background

ALK2 ALK2 YBL009W

ChrII:207194 to 209224 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2031 207194..209224

Protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; phosphorylated in response to DNA damage; ALK2 has a paralog, ALK1, that arose from the whole genome duplication; similar to mammalian haspins

BCK2 BCK2 YER167W CTR7

ChrV:518216 to 520771 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2556 518216..520771

Serine/threonine-rich protein involved in PKC1 signaling pathway; protein kinase C (PKC1) signaling pathway controls cell integrity; overproduction suppresses pkc1 mutations

CK2 subunit CKB1 YGL019W CK2 subunit, casein kinase 2 regulatory subunit CKB1

ChrVII:458156 to 458992 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..837 458156..458992

Beta regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases

CK2 subunit CKA1 YIL035C CK2 subunit, casein kinase 2 catalytic subunit CKA1

ChrIX:288908 to 287790 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1119 288908..287790

Genetic position: -29 cM

Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching

CK2 subunit CKB2 YOR039W CK2 subunit, casein kinase 2 regulatory subunit CKB2

ChrXV:405768 to 406544 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..777 405768..406544

Beta' regulatory subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase

CK2 subunit CKA2 YOR061W YOR29-12, CK2 subunit, casein kinase 2 catalytic subunit CKA2

ChrXV:441534 to 442553 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1020 441534..442553

Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching

CMK2 CMK2 YOL016C

ChrXV:296120 to 294777 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1344 296120..294777

Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication

CTK2 CTK2 YJL006C

ChrX:424109 to 423138 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..972 424109..423138

Beta subunit of C-terminal domain kinase I (CTDK-I); which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; relocalizes to the cytosol in response to hypoxia

CYK2 HOF1 YMR032W CYK2

ChrXIII:335298 to 337307 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2010 335298..337307

SH3 domain-containing protein required for cytokinesis; localized to bud neck; phosphorylated by Dbf2p; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p

DAK2 DAK2 YFL053W

ChrVI:23423 to 25198 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1776 23423..25198

Dihydroxyacetone kinase; required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation

DSK2 DSK2 YMR276W

ChrXIII:818827 to 819948 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1122 818827..819948

Nuclear-enriched ubiquitin-like polyubiquitin-binding protein; required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle; involved in proteolysis; interacts with the proteasome; protein abundance increases in response to DNA replication stress

FPK2 KIN82 YCR091W FPK2

ChrIII:274404 to 276566 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2163 274404..276566

Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases) Lem3p-Dnf1p/Dnf2p; KIN82 has a paralog, FPK1, that arose from the whole genome duplication

HEK2 HEK2 YBL032W KHD1

ChrII:160184 to 161329 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1146 160184..161329

RNA binding protein involved in asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K

HSK2 DAD4 YDR320C-A HSK2

ChrIV:1108498 to 1108280 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..219 1108498..1108280

Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

HXK2 HXK2 YGL253W HEX1, HKB, SCI2, hexokinase 2

ChrVII:23935 to 25395 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1461 23935..25395

Genetic position: -167 cM

Hexokinase isoenzyme 2; catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at serine-14 by protein kinase Snf1p and protein phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; HXK2 has a paralog, HXK1, that arose from the whole genome duplication

IPK2 ARG82 YDR173C ARGR3, IPK2, ARGRIII, inositol polyphosphate multikinase

ChrIV:811632 to 810565 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1068 811632..810565

Genetic position: 95 cM

Inositol polyphosphate multikinase (IPMK); sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes

MAK20 MAK20 MAK20

MAK21 MAK21 YDR060W NOC1

ChrIV:570649 to 573726 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3078 570649..573726

Constituent of 66S pre-ribosomal particles; required for large (60S) ribosomal subunit biogenesis; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein

MAK22 MAK22 MAK22

MAK24 MAK24 MAK24

ChrVII

Genetic position: -56 cM

MAK26 MAK26 MAK26

ChrXIV

Genetic position: -114 cM

MAK27 MAK27 MAK27

ChrXIII

Genetic position: 156 cM

MKK2 MKK2 YPL140C LPI6, SSP33

ChrXVI:289034 to 287514 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1521 289034..287514

MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication

PFK2 PFK2 YMR205C 6-phosphofructokinase subunit beta

ChrXIII:674766 to 671887 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2880 674766..671887

Genetic position: 132 cM

Beta subunit of heterooctameric phosphofructokinase; involved in glycolysis; indispensable for anaerobic growth; activated by fructose-2,6-bisphosphate and AMP; mutation inhibits glucose induction of cell cycle-related genes

PFK26 PFK26 YIL107C PFK2, PFK-2

ChrIX:165761 to 163278 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2484 165761..163278

6-phosphofructo-2-kinase; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A

PFK27 PFK27 YOL136C PFK-2

ChrXV:68754 to 67561 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1194 68754..67561

6-phosphofructo-2-kinase; catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A

PSK2 PSK2 YOL045W

ChrXV:243497 to 246802 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3306 243497..246802

PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication

PTK2 PTK2 YJR059W STK2

ChrX:545787 to 548243 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2457 545787..548243

Putative serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication

PYK2 PYK2 YOR347C pyruvate kinase PYK2

ChrXV:986462 to 984942 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1521 986462..984942

Pyruvate kinase; appears to be modulated by phosphorylation; transcription repressed by glucose, and Pyk2p may be active under low glycolytic flux; PYK2 has a paralog, CDC19, that arose from the whole genome duplication

RCK2 RCK2 YLR248W CLK1, CMK3

ChrXII:634252 to 636084 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1833 634252..636084

Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication

SLK2 SLT2 YHR030C BYC2, MPK1, SLK2, LYT2, mitogen-activated serine/threonine-protein kinase SLT2

ChrVIII:170344 to 168890 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1455 170344..168890

Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, cell cycle progression, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to phagophore assembly site (PAS); plays a role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway; SLT2 has a paralog, KDX1, that arose from the whole genome duplication

SOK2 SOK2 YMR016C

ChrXIII:305593 to 303236 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2358 305593..303236

Nuclear protein that negatively regulates pseudohyphal differentiation; plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; relocalizes to the cytosol in response to hypoxia; SOK2 has a paralog, PHD1, that arose from the whole genome duplication

SSK2 SSK2 YNR031C

ChrXIV:685433 to 680694 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..4740 685433..680694

MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication

SSK22 SSK22 YCR073C

ChrIII:246583 to 242588 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3996 246583..242588

MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication

tA(AGC)K2 tA(AGC)K2

ChrXI:517988 to 518060 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..73 517988..518060

Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon AGC (converted to IGC in the mature tRNA), decodes GCU and GCC codons into alanine, one of 16 nuclear tRNAs for alanine

TPK2 TPK2 YPL203W PKA2, YKR1, PKA3, cAMP-dependent protein kinase catalytic subunit TPK2

ChrXVI:166256 to 167398 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1143 166256..167398

Genetic position: -120 cM

cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia

TRK2 TRK2 YKR050W RPD2

ChrXI:527815 to 530484 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2670 527815..530484

Genetic position: 15 cM

Component of the Trk1p-Trk2p potassium transport system; contributes to K(+) supply and maintenance of plasma-membrane potential; TRK2 has a paralog, TRK1, that arose from the whole genome duplication

tV(AAC)K2 tV(AAC)K2

ChrXI:379680 to 379753 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..74 379680..379753

Valine tRNA (tRNA-Val), predicted by tRNAscan-SE analysis

YCK2 YCK2 YNL154C

ChrXIV:345276 to 343636 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1641 345276..343636

Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; YCK2 has a paralog, YCK1, that arose from the whole genome duplication

YOK22 TOM7 YNL070W MOM7, YOK22

ChrXIV:493366 to 493548 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..183 493366..493548

Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex

YPK2 YPK2 YMR104C YKR2

ChrXIII:475453 to 473420 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2034 475453..473420

Protein kinase similar to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK; YPK2 has a paralog, YPK1, that arose from the whole genome duplication