JSN1/YJR091C Summary Help

JSN1 BASIC INFORMATION

Standard Name JSN1
Systematic Name YJR091C
Alias PUF1
Feature Type ORF, Verified
Description Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl (1, 2, 3, 4)
Name Description Just Say No 1
GO Annotations All JSN1 GO evidence and references
    View Computational GO annotations for JSN1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All JSN1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions JSN1 All interactions details and references
52 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 2
  • Co-localization: 1
  • PCA: 1
  • Protein-RNA: 2
  • Reconstituted Complex: 1
  • Two-hybrid: 23
Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 8
  • Phenotypic Suppression: 9
Sequence Information
ChrX:598328 to 595053 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3276 598328..595053 2009-02-18 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003851

JSN1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for JSN1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for JSN1]

1) Machin NA, et al.  (1995) Microtubule stability in budding yeast: characterization and dosage suppression of a benomyl-dependent tubulin mutant. Mol Biol Cell 6(9):1241-59
2) Olivas W and Parker R  (2000) The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast. EMBO J 19(23):6602-11
3) Gerber AP, et al.  (2004) Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol 2(3):E79
4) Fehrenbacher KL, et al.  (2005) A role for Jsn1p in recruiting the Arp2/3 complex to mitochondria in budding yeast. Mol Biol Cell 16(11):5094-102