JHD1/YER051W Summary Help

Standard Name JHD1 1, 2
Systematic Name YER051W
Feature Type ORF, Verified
Description JmjC domain family histone demethylase specific for H3-K36; similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe (1)
Name Description JmjC domain-containing Histone Demethylase 1
Gene Product Alias JHDM1 1 , KDM2 3
Chromosomal Location
ChrV:254656 to 256134 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All JHD1 GO evidence and references
  View Computational GO annotations for JHD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Large-scale survey
null
Resources
14 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-Luminescence: 4
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3

Genetic Interactions
  • Negative Genetic: 4
  • Phenotypic Suppression: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 492
Molecular Weight (Da) 56,530
Isoelectric Point (pI) 6.74
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:254656 to 256134 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1479 254656..256134 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000853
References cited on this page View Complete Literature Guide for JHD1
1) Tsukada YI, et al.  (2006) Histone demethylation by a family of JmjC domain-containing proteins. Nature 439(7078):811-6
2) Shi X, et al.  (2007) Proteome-wide Analysis in Saccharomyces cerevisiae Identifies Several PHD Fingers as Novel Direct and Selective Binding Modules of Histone H3 Methylated at Either Lysine 4 or Lysine 36. J Biol Chem 282(4):2450-5
3) Allis CD, et al.  (2007) New nomenclature for chromatin-modifying enzymes. Cell 131(4):633-6