ITT1/YML068W Summary Help

Standard Name ITT1
Systematic Name YML068W
Feature Type ORF, Verified
Description Protein that modulates the efficiency of translation termination; interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins (1)
Chromosomal Location
ChrXIII:137550 to 138944 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ITT1 GO evidence and references
  View Computational GO annotations for ITT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
null
Large-scale survey
null
overexpression
Resources
43 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • PCA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 3
  • Dosage Rescue: 1
  • Negative Genetic: 15
  • Phenotypic Enhancement: 1
  • Positive Genetic: 15
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 464
Molecular Weight (Da) 54,095
Isoelectric Point (pI) 5.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:137550 to 138944 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1395 137550..138944 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004533
References cited on this page View Complete Literature Guide for ITT1
1) Urakov VN, et al.  (2001) Itt1p, a novel protein inhibiting translation termination in Saccharomyces cerevisiae. BMC Mol Biol 2():9