Standard Name	IRC7 1
Systematic Name	YFR055W
Feature Type	ORF, Uncharacterized
Description	Beta-lyase involved in the production of thiols; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner and by copper levels in a Mac1-dependent manner (1, 2, 3, 4, 5)
Name Description	Increased Recombination Centers 1

Chromosomal Location	ChrVI:264204 to 265226 | ORF Map | GBrowse

	View Computational GO annotations for IRC7
Molecular Function
Manually curated	cysteine-S-conjugate beta-lyase activity (IDA, IMP)
Biological Process
Manually curated	L-cysteine catabolic process to pyruvate (IDA, IMP) sulfur compound metabolic process (IDA, IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Classical genetics
null	3-sulfanylhexan-1-ol excretion: decreased 4-methyl-4-sulfanylpentan-2-one excretion: decreased 4-mercapto-4-methylpentan-2-one excretion: decreased viable
Large-scale survey
null	competitive fitness: decreased haploinsufficient metal resistance: decreased mitotic recombination: increased Rad52-YFP distribution: increased resistance to glycolaldehyde: decreased resistance to benzo[a]pyrene: decreased resistance to cycloheximide: decreased resistance to streptomycin: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	21 total interaction(s) for 21 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1
Genetic Interactions	Negative Genetic: 17 Positive Genetic: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:264204 to 265226 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1023 264204..265226 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001952