IRC3/YDR332W Summary Help

Standard Name IRC3 1
Systematic Name YDR332W
Feature Type ORF, Verified
Description Putative RNA helicase of the DEAH/D-box family; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion (1, 2)
Name Description Increased Recombination Centers 1
Chromosomal Location
ChrIV:1131001 to 1133070 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All IRC3 GO evidence and references
  View Computational GO annotations for IRC3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Classical genetics
null
Large-scale survey
null
unspecified
Resources
59 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Two-hybrid: 7

Genetic Interactions
  • Negative Genetic: 19
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 9
  • Synthetic Lethality: 17

Resources
Expression Summary
histogram
Resources
Length (a.a.) 689
Molecular Weight (Da) 78,546
Isoelectric Point (pI) 9.49
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1131001 to 1133070 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2070 1131001..1133070 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002740
References cited on this page View Complete Literature Guide for IRC3
1) Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
2) de la Cruz J, et al.  (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8