IOC2/YLR095C Summary Help

Standard Name IOC2 1
Systematic Name YLR095C
Feature Type ORF, Verified
Description Subunit of the Isw1b complex; exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing; contains a PHD finger motif; other complex members are Isw1p and Ioc4p (1, 2)
Name Description Iswi One Complex 1
Chromosomal Location
ChrXII:332115 to 329677 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All IOC2 GO evidence and references
  View Computational GO annotations for IOC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
repressible
Resources
54 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 25
  • Positive Genetic: 4
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 812
Molecular Weight (Da) 93,445
Isoelectric Point (pI) 5.58
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:332115 to 329677 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2439 332115..329677 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004085
References cited on this page View Complete Literature Guide for IOC2
1) Vary JC Jr, et al.  (2003) Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol 23(1):80-91
2) Morillon A, et al.  (2003) Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115(4):425-35