INM2/YDR287W Summary Help

Standard Name INM2 (see Nomenclature conflict Note)
Systematic Name YDR287W
Feature Type ORF, Verified
Description Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy (1)
Name Description INositol Monophosphatase 2
Chromosomal Location
ChrIV:1035995 to 1036873 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All INM2 GO evidence and references
  View Computational GO annotations for INM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Pathways
Classical genetics
overexpression
Large-scale survey
null
Resources
22 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Negative Genetic: 15
  • Positive Genetic: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1035995 to 1036873 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..879 1035995..1036873 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002695

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
IMP2Nomenclature conflictThe gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W.
IMP2'Nomenclature conflictThe gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W.
References cited on this page View Complete Literature Guide for INM2
1) Lopez F, et al.  (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64
2) Murray M and Greenberg ML  (2000) Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Mol Microbiol 36(3):651-61