| Standard Name | INM2 (see Nomenclature conflict Note) |
|---|---|
| Systematic Name | YDR287W |
| Feature Type | ORF, Verified |
| Description | Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy (1) |
| Name Description | INositol Monophosphatase 2 |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All INM2 GO evidence and references
| View Computational GO annotations for INM2 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
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| Pathways |
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Mutant phenotypes All INM2 Phenotype evidence and references
| Classical genetics | |
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| overexpression | |
| Large-scale survey | |
| null |
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| Resources |
interactions All INM2 Interaction evidence and references
| 22 total interaction(s) for 18 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All INM2 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000002695 |
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NOMENCLATURE CONFLICT NOTE
| Name | Relevance | Description |
|---|---|---|
| IMP2 | Nomenclature conflict | The gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W. |
| IMP2' | Nomenclature conflict | The gene name IMP2 has been used to refer to the transcriptional coactivator IMP2'/YIL154C, the inositol monophosphatase INM2/YDR287W, and the mitochondrial inner membrane peptidase IMP2/YMR035W. |
References cited on this page View Complete Literature Guide for INM2
| 1) | Lopez F, et al. (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64 |
| 2) | Murray M and Greenberg ML (2000) Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Mol Microbiol 36(3):651-61 |




