IMA4/YJL221C Summary

IMA4/YJL221C Summary

Standard Name	IMA4 1, 2
Systematic Name	YJL221C
Alias	FSP2
Feature Type	ORF, Verified
Description	Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima4p overexpression allows the ima1 null mutant to grow on isomaltose; identical to IMA3 (1, 2, 3, 4)
Name Description	IsoMAltase 1, 2

Chromosomal Location	ChrX:18536 to 16767 \| ORF Map \| GBrowse
	Note: this feature is encoded on the Crick strand.

Gene Ontology Annotations All IMA4 GO evidence and references

	View Computational GO annotations for IMA4
Molecular Function
Manually curated	oligo-1,6-glucosidase activity (IDA, IMP)
Biological Process
Manually curated	disaccharide catabolic process (IGI)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant phenotypes All IMA4 Phenotype evidence and references

Large-scale survey
overexpression	resistance to sirolimus: increased
Resources	PROPHECY \| SCMD \| ScreenTroll \| Yeast Fitness Database

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Protein Information All IMA4 Protein evidence and references

Localization	YeastRC \| YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP \| YeastRC
Homologs	Ashbya (AGD) \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrX:18536 to 16767 | |

Note: this feature is encoded on the Crick strand.

SGD ORF map

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1770	18536..16767	1996-07-31	1996-07-31

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000003757

References cited on this page View Complete Literature Guide for IMA4

1)	Teste MA, et al. (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24
2)	Naumoff DG and Naumov GI (2010) Discovery of a novel family of alpha-glucosidase IMA genes in yeast Saccharomyces cerevisiae. Dokl Biochem Biophys 432():114-6
3)	Backhus LE, et al. (2001) Functional genomic analysis of a commercial wine strain of Saccharomyces cerevisiae under differing nitrogen conditions. FEMS Yeast Res 1(2):111-25
4)	Brown CA, et al. (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903