IMA3/YIL172C Summary Help

Standard Name IMA3 1, 2
Systematic Name YIL172C
Feature Type ORF, Verified
Description Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose; lower activitiy and thermostability in vitro than Ima2p despite sequence difference of only 3 amino acids; cleaves alpha-1,3 linkage of nigerose and turanose, but not alpha-1,5 of leucrose; identical to IMA4 (1, 2, 3, 4)
Name Description IsoMAltase 1, 2
Chromosomal Location
ChrIX:18553 to 16784 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All IMA3 GO evidence and references
  View Computational GO annotations for IMA3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
5 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Biochemical Activity: 3
  • Two-hybrid: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 589
Molecular Weight (Da) 68,698
Isoelectric Point (pI) 5.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:18553 to 16784 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1770 18553..16784 1994-12-10 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001434
References cited on this page View Complete Literature Guide for IMA3
1) Teste MA, et al.  (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24
2) Naumoff DG and Naumov GI  (2010) Discovery of a novel family of alpha-glucosidase IMA genes in yeast Saccharomyces cerevisiae. Dokl Biochem Biophys 432():114-6
3) Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903
4) Deng X, et al.  (2014) Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae. FEBS Open Bio 4():200-12