IKS1/YJL057C Summary Help

Standard Name IKS1 1
Systematic Name YJL057C
Feature Type ORF, Verified
Description Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p (1, 2, 3, 4, 5)
Chromosomal Location
ChrX:330121 to 328118 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All IKS1 GO evidence and references
  View Computational GO annotations for IKS1
Molecular Function
High-throughput
Biological Process
High-throughput
Cellular Component
Manually curated
Regulators 3 genes
Resources
Large-scale survey
null
Resources
78 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 12
  • Reconstituted Complex: 39
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 6
  • Positive Genetic: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 667
Molecular Weight (Da) 75,327
Isoelectric Point (pI) 6.42
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:330121 to 328118 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2004 330121..328118 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003593
References cited on this page View Complete Literature Guide for IKS1
1) Rieger KJ, et al.  (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86
2) Burchett SA, et al.  (2002) Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. J Biol Chem 277(25):22156-67
3) Mollapour M, et al.  (2004) Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast 21(11):927-46
4) Ptacek J, et al.  (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84
5) Sakaki K, et al.  (2003) Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. J Biochem 134(3):373-84