IDP3/YNL009W Summary

IDP3 BASIC INFORMATION

Standard Name	IDP3
Systematic Name	YNL009W
Feature Type	ORF, Verified
Description	Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids (1)
Name Description	Isocitrate Dehydrogenase, NADP-specific

GO Annotations	All IDP3 GO evidence and references
	View Computational GO annotations for IDP3
Molecular Function
Manually curated	isocitrate dehydrogenase (NADP+) activity (TAS)
Biological Process
Manually curated	fatty acid beta-oxidation (IMP) isocitrate metabolic process (TAS) NADPH regeneration (TAS)
Cellular Component
Manually curated	cytoplasm (IDA) peroxisome (IDA, TAS)
High-throughput	cytoplasm (IDA) mitochondrion (IDA)

Pathways	superpathway of glutamate biosynthesis

Mutant Phenotype	All IDP3 Phenotype details and references
Classical genetics
null	utilization of carbon source: decreased utilization of carbon source: absent
Large-scale survey
null	replicative lifespan: increased viable

Interactions	IDP3 All interactions details and references
	10 total interaction(s) for 9 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 2
Genetic Interactions	Synthetic Growth Defect: 3 Synthetic Lethality: 1

Sequence Information

ChrXIV:614823 to 616085 | |

Last Update

Coordinates: 2010-01-05 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1263	614823..616085	2010-01-05	1997-01-28

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004954

IDP3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for IDP3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for IDP3]

1)	Henke B, et al. (1998) IDP3 encodes a peroxisomal NADP-dependent isocitrate dehydrogenase required for the beta-oxidation of unsaturated fatty acids. J Biol Chem 273(6):3702-11

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