IDP1/YDL066W Summary Help

Standard Name IDP1 1
Systematic Name YDL066W
Feature Type ORF, Verified
Description Mitochondrial NADP-specific isocitrate dehydrogenase; catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes (1, 2)
Name Description Isocitrate Dehydrogenase, NADP-specific 1
Chromosomal Location
ChrIV:334835 to 336121 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All IDP1 GO evidence and references
  View Computational GO annotations for IDP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
60 total interaction(s) for 41 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 27
  • Positive Genetic: 2
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 428
Molecular Weight (Da) 48,190
Isoelectric Point (pI) 9.45
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:334835 to 336121 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1287 334835..336121 2004-02-11 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002224
References cited on this page View Complete Literature Guide for IDP1
1) Haselbeck RJ and McAlister-Henn L  (1991) Isolation, nucleotide sequence, and disruption of the Saccharomyces cerevisiae gene encoding mitochondrial NADP(H)-specific isocitrate dehydrogenase. J Biol Chem 266(4):2339-45
2) Haselbeck RJ and McAlister-Henn L  (1993) Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases. J Biol Chem 268(16):12116-22