HXT7/YDR342C Summary Help

Standard Name HXT7 1
Systematic Name YDR342C
Feature Type ORF, Verified
Description High-affinity glucose transporter; member of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels; HXT7 has a paralog, HXT4, that arose from the whole genome duplication (2, 3, 4)
Name Description HeXose Transporter 1
Chromosomal Location
ChrIV:1155928 to 1154216 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gene Ontology Annotations All HXT7 GO evidence and references
  View Computational GO annotations for HXT7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
53 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Affinity Capture-RNA: 2
  • Co-fractionation: 3
  • Co-purification: 1
  • PCA: 2

Genetic Interactions
  • Negative Genetic: 6
  • Phenotypic Enhancement: 6
  • Positive Genetic: 7

Expression Summary
Length (a.a.) 570
Molecular Weight (Da) 62,735
Isoelectric Point (pI) 7.7
Phosphorylation PhosphoGRID | PhosphoPep Database
sequence information
ChrIV:1155928 to 1154216 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Most Recent Updates
Coordinates Sequence
CDS 1..1713 1155928..1154216 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000002750
References cited on this page View Complete Literature Guide for HXT7
1) Reifenberger E, et al.  (1995) Identification of novel HXT genes in Saccharomyces cerevisiae reveals the impact of individual hexose transporters on glycolytic flux. Mol Microbiol 16(1):157-67
2) Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
3) Reifenberger E, et al.  (1997) Kinetic characterization of individual hexose transporters of Saccharomyces cerevisiae and their relation to the triggering mechanisms of glucose repression. Eur J Biochem 245(2):324-33
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61